Hair Restoration
PLATELET-RICH FIBRIN MATRIX (PRFM)
Platelet-rich fibrin matrix (PRFM) is a regenerative therapy used in hair restoration procedures.
PRFM starts with the collection of a small sample of your blood. This blood is then processed to isolate the platelets. Platelets are tiny blood cells that play a crucial role in wound healing, and they contain growth factors, which help stimulate tissue repair and regeneration. The isolated platelets are combined with a fibrin matrix. Fibrin matrix serves as a scaffold that helps hold the platelets in place and promotes their release of growth factors over time. Once the PRFM is prepared, it is injected directly into the scalp; The growth factors released by the platelets help rejuvenate dormant hair follicles, increase blood flow to the scalp, and promote the growth phase of the hair cycle.
RADIOFREQUENCY (RF) MICRONEEDLING AND GROWTH-FACTOR THERAPY
Sylfirm X radiofrequency (RF) microneedling combined with exosome use is an advanced technique used in hair restoration procedures. RF microneedling is a minimally invasive cosmetic procedure that uses tiny needles to create controlled micro-injuries in the skin's surface. These micro-injuries trigger the body's natural healing process, stimulating collagen production and rejuvenating the skin. When applied to the scalp, RF microneedling can improve blood circulation, promote cell regeneration, and enhance the health of hair follicles.
Platelet-derived growth factors (PDGF) are naturally found in the body to promote wound healing. Ariessence Pure PDGF (Platelet-Derived Growth Factor) harnesses the power of nature’s most prolific protein for skin and hair rejuvenation. Pure PDGF+ contains up A 1000 (or more) fold times the growth factor concentration of platelet-rich solutions. The high concentration of growth factors in platelet-derived growth factors promote hair regrowth by stimulating stem cells in dormant hair follicle to grow new hair. Platelet-derived growth factors can reverse hair loss and stimulate natural hair regrowth. Additionally, treatments accelerate tissue regeneration and healing, and improve the blood supply to the scalp which delivers nutrients for hair growth.
NANOFAT GRAFTING FOR HAIR RESTORATION
Nanofat hair restoration involves the use of a patient’s own processed fat cells that are placed by injection into the scalp to stimulate skin rejuvenation and help facilitate hair growth. Evidence suggests that fat grafts can be effective in stimulating hair growth when placed into the hair follicle, like the PRP hair restoration process. Candidates for nanofat hair restoration are those who experience hair thinning, a receding hairline, or balding due to aging or other factors and some forms of scarring hair loss. Nanofat hair restoration can be used with hair restoration techniques like PRP or hair transplantation.
Nanofat hair restoration begins by obtaining fat cells by liposuction. A small amount of fat (40 to 100cc) is harvested, typically on the abdomen, thighs, or hips. This is done under local anesthesia. The fat cells are then processed and purified and placed into a syringe. Small injections of the fat cells will then be placed in the scalp where thinning and balding have occurred. Processed fat cells release growth factors that increase stem cell activity within the hair follicle, Fat not only contains growth factors, but it also: reduces the concentration of androgens like testosterone in tissue, increases vascularity thus increasing blood flow, and lastly suppresses inflammation which can help prevent hair loss. This procedure is typically performed once though some patients may require 2 sessions over 6-12 months.
INTRALESIONAL DUTASTERIDE
Intralesional dutasteride is a treatment approach used in hair restoration for individuals experiencing hair loss, particularly in cases of androgenetic alopecia (pattern baldness). Dutasteride is a 5-alpha reductase inhibitor, and it works by blocking the enzyme 5-alpha reductase, which converts testosterone into dihydrotestosterone (DHT). DHT is a potent androgen hormone that can shrink hair follicles, leading to hair thinning and eventual hair loss in individuals genetically predisposed to androgenetic alopecia.
Intralesional dutasteride involves injecting medications directly into the affected area. This localized delivery method allows for a more targeted and potent effect on the hair follicles while minimizing systemic exposure to the medication.